Translational Insight Scientist (Biomedical)

Position: Translational Insight Scientist (Biomedical)

Location: Singapore
Department: Research & Development
Reports To: Senior Scientist / Bioengineering Lead
Job Type: Full-time
Experience Level: Mid-Level

Position Overview

We are seeking a motivated scientist with a background in biotechnology or life sciences to support the development and application of Organ-on-a-Chip (OoC) and organoid models for advanced drug evaluation and biological inference. The role focused on building and characterizing microphysiological systems, including 3D cultures and fluidic devices with a supportive interface to our computational biology team.

The ideal candidate will be passionate about advancing human-relevant models for drug discovery, toxicology, and systems biology, using cutting-edge biotech platforms such as engineered tissues, organoids, and lab-on-a-chip devices.

Key Responsibilities

• Develop, maintain, and validate Organ-on-a-Chip (OoC) and organoid models to support drug testing, pharmacological studies, and response profiling.
• Perform functional and biochemical assays including TEER, ELISA, cytokine profiling, and viability/toxicity assessments to characterize model behavior.
• Handle human-derived primary and stem cell cultures, establish 3D microenvironments, and operate fluidic systems in chip and scaffold platforms.
• Optimize experimental protocols and troubleshoot biological and device performance across organoid and OoC systems.
• Interface with computational biology and AI teams by providing high-quality biological data and mechanistic context for in silico validation and inference.
• Interpret results within biological pathways involving barrier integrity, inflammatory responses, enzymatic activity, and cellular stress.
Keep abreast of scientific developments in organoid biology, organ-on-chip, and translational microphysiological modeling

Minimum Qualifications

• Bachelor’s degree (B.Sc. or equivalent) in a relevant life sciences or bioengineering field
• Hands-on experience in cell culture, tissue engineering, or lab-on-a-chip systems.
• Familiarity with biological datasets (e.g., gene expression, imaging) and capacity to interpret them in collaboration with data specialists.
• Strong experimental and laboratory skills, with attention to reproducibility and detail.
Effective communication skills and a collaborative approach to problem-solving

Preferred Qualifications

• Prior experience working with Organ-on-a-Chip, microfluidic platforms, or advanced in vitro models preferred.
• Conceptual understanding of bioinformatics tools (e.g., omics data, pathway mapping) from a biological user perspective.
Experience in cross-functional teams involving data science, pharmacology, or systems biology

What We Offer

• A forward-thinking biotech environment addressing unmet needs in drug development and toxicology.
• Opportunities to collaborate with global experts in bioengineering, computational biology, and pharmacology.
• Competitive compensation and benefits package.
Career development opportunities within the growing field of translational human-relevant research

How to Apply

Please submit your resume and a brief cover letter (including salary expectations) to:
[email protected]
Make sure to highlight your biotech experience and interest in microphysiological systems.