Research Officer (DMOSSV)

National Cancer Centre of Singapore Pte Ltd

Job Category: Research

Posting Date: 29 Jun 2026

About the Position

We are seeking a highly motivated Research Officer to join our translational research team working on cutting-edge CAR T-cell therapies for gastrointestinal cancers. This role offers an excellent opportunity to contribute to innovative cancer immunotherapy research in a dynamic and supportive academic-clinical environment.

Key Responsibilities

  • Perform in vivo studies including tumor implantation and whole-body bioluminescence imaging of tumor-bearing NSG mice using the IVIS Spectrum system.
  • Expand and maintain human immune cells and organoids.
  • Conduct retroviral transduction for CAR T-cell generation.
  • Perform multi-parameter flow cytometry analysis.
  • Execute tumor cytotoxicity assays using the Tecan Infinite 200 Pro plate reader.
  • Conduct live-cell imaging of 3D tumor spheroids using the S3 IncuCyte system.
  • Support laboratory biosafety management, equipment maintenance, and ordering of experimental reagents and materials.

Requirements

  • Bachelor’s Degree in Science, Biomedicine (BSc), or a related field.
  • Strong passion for tumor immunology, immune evasion mechanisms, immune activation and tolerance, protein structure and function, and immune cell engineering.
  • Diligent, self-motivated, conscientious, and team-oriented.
  • Detail-oriented with a strong sense of responsibility and ownership.
  • Excellent communication skills, along with strong analytical and critical thinking abilities.

What We Offer

  • Opportunity to work on impactful, translational cancer immunotherapy.

- Access to advanced technologies - In vivo imaging system, IncuCyte live cell spheroid imaging, flow cytometry analysis, Olink proteomics, Pixelgen functional interactomics.

  • This is a full-time contract position. Candidates with prior hands-on experience in mouse models and whole body IVIS imaging system are strongly encouraged to apply.

Contact: Dr SEOW See-Voon

Email: ***email_hidden***

Req ID: 4953